I checked on this to make sure I'm not just blindly inventing complications. Let's pretend the season ended today and the BTT seeded out based on the standings.
As the #2, we'd face the winner of Purdue-Penn State. Purdue isn't currently projected in and that'd only be our second game against PSU. We could theoretically then face Rutgers, MSU, or Maryland for the third time if we were to advance to the title game.
I'll just use one bracket to illustrate what could happen if we were to 1) hypothetically beat PSU, 2) beat Rutgers and then 3) lose to Maryland in the BTT title game.
Jerry Palm currently has Maryland as a 3, MSU as a 4, PSU as a 4, us as a 5, Rutgers as a 6. We're currently in Maryland's bracket (the East), and if that hypothetical happened we'd have to move (because of the 3 games against the Terps), but:
-We couldn't keep our seed and move to the South, because Penn State is the 4 there and you can't play a team you've already played twice in the second round
-We couldn't keep our seed and move to the West, because MSU is the 4 there and the same thing applies
-We couldn't move to the Midwest at all, because Rutgers is there and we've played them three times already.
So in this scenario, our seed would have to change (or somebody else's would) solely because there's nowhere for us to go as a 5-seed.