This is the kind of game that the United Center game has to be. Little doubt that this will be a big game with a great atmosphere.
Regarding "road neutral" games that could be a return for a United Center game, with conference consolidation we really don't have a lot of great options. Here are a few that spring to mind that could generate excitement for a game at the United Center (example - I don't see Cal or Stanford as programs that would generate a lot of buzz at the United Center in exchange for a game at Chase Center in San Francisco).
UConn - MSG (but that's really like a second home for UConn)
Florida - Tampa or Orlando
Tennessee - Memphis, Atlanta or Nashville
Alabama - Birmingham
Auburn (but not until Bruce Pearl is gone - Illinois should do nothing to benefit him) - Birmingham or Atlanta
Texas - Dallas
Baylor - Houston or Dallas
Marquette - Annual Bragging Rights style game
Arizona - Phoenix
Kansas - Kansas City
Iowa State - Kansas City
Other than that, I don't really see programs that would generate enough buzz to put 20,000 people in the United Center. Baylor and Iowa State might not even be big enough to do that, but I figure there are a lot of Iowa State alums in the Chicago area. I'd rather just do traditional on-campus home and homes with other power conference programs like Virginia, Georgia, Cal, Stanford, etc. I also am pretty sure Duke and North Carolina would not do a game in Charlotte to return a United Center game, so if we have to go to Chapel Hill or Cameron Indoor make them play in Champaign.