CONCACAF is changing its qualifying format for 2022 with the video here explaining the change:
In short, it's going to be like this. The Hex will still be played but will only involve the top 6 teams in the FIFA World rankings (which as of now, would be Mexico, USA, Costa Rica, Jamaica, Honduras and El Salvador) after the FIFA window of June 2020. For the remaining teams in the confederation (teams 7-35), they'll go into a group stage comprised of eight groups (five groups of four and three groups of three). The first place finishers of the eight groups will then go into a single elimination knockout stage with quarterfinals, semifinals, and finals played in a home-and-home format. The winner of the knockout stage will then play the 4th place finisher in the Hex to determine the CONCACAF representative in the intercontinental playoff.