He could for sure, it would just look different than what we've been doing. The most natural thing to do is get another shooter to keep the offense humming, and figure it out defensively.
That being said... A lineup of Big Z, Ty, and pick whatever 3 guards you want would be fun to watch. Could switch 1-4 with Z as the rim protector and offensively you can really run.
Tempo is going to be the thing to watch for me. Don't forget we started the season trying to play pretty fast. Got slower and slower as the season went along. But I do think Brad's natural mindset is to attack and be aggressive. Wouldn't be surprised if we try to pick up the tempo again, but let's see how the roster finishes up first.